Job Purpose

To make a leading contribution to the project “Defining interplay between TREM2pos tissue-resident macrophages and GAS6pos interstitial fibroblasts in restoring tissue homeostasis”, funded by UKRI-BBSRC UK. The successful candidate will work under the supervision of Professor Mariola Kurowska-Stolarska (Principal Investigator) at the University of Glasgow**, in collaboration with postdoctoral fellows and their supervisors: Professor Stefano Alivernini (collaborator) at Gemelli Hospital in Rome, and Professor Christopher Buckley (Co-investigator) at the University of Oxford.

The candidate will lead a specific research stream within this project, which aims to deepen our understanding of the tissue mechanisms responsible for re-establishing self-maintained homeostasis after inflammation. The project follows a bedside-to-bench-and-back approach, utilizing human tissue single-cell and spatial multi-omics at disease remission (inflammation resolution), human tissue organoids, and the use and generation of unique transgenic mouse models. The candidate will also contribute to the preparation and submission of research publications and grant proposals and will take responsibility for managing the human tissue biobank and/or mouse strains that support the project.

Main Duties and Responsibilities

1. Take a leading role in planning and conducting assigned research stream, individually or jointly, in accordance with the project deliverables and the Kurowska-Stolarska & Alivernini group, the Infection & Immunity School, and the MVLS College research strategy

2. Document all research outputs, including raw data, and conduct data analysis and interpretation. Maintain accurate records and databases and prepare technical and progress reports and papers as requested by the Principal Investigator, in accordance with the Data Management Plan of the Kurowska-Stolarska & Alivernini group and the University of Glasgow.

3. Establish and maintain your research profile and reputation, as well as that of the Kurowska-Stolarska & Alivernini group, the Infection & Immunity School, and the MVLS College at the University of Glasgow. This includes building and sustaining a track record of internationally competitive publications in high-quality, peer-reviewed journals, enhancing research impact in terms of economic and societal benefit (particularly in advancing arthritis prevention), and gathering indicators of esteem.

4. Regularly survey the research literature and environment, understand the research challenges associated with the project & subject area, & develop/implement a suitable research strategy.

5. Presentation of work at international and national conferences, at internal and external seminars, and workshops to develop and enhance our research profile.

6. Take a leading role in the identification of potential funding sources and to assist the PI in the

development of proposals to secure funding from internal and external bodies to support future research.

7. Take a leading role in developing and maintaining collaborations with colleagues across the research groups in the School of Infection and Immunity, MVLS College, The University and wider community (e.g. Academic and Industrial Partners).

8. Take a leading role in team/group meetings/seminars/workshops and School research group activities to enhance the wider knowledge, outputs, and culture of the Research Group/School/College.

9. Take the lead in the organisation, supervision, mentoring and training of undergraduate

and/or postgraduate students and less experienced members of the project team to ensure their effective development.

10. Perform administrative tasks related to the activities of the research group, including managing mice stains, human tissue biobank, lab orders and keeping the record of expenditure of the grant.

11. Make a leading contribution to Teaching activities (e.g. demonstrating at labs run by the PI, running journal clubs for undergraduates) and associated admin as requested by the Principal Investigator.

12. Keep up to date with current knowledge and recent advances in the field of Immunology, resolution of inflammation and tissue resident macrophage biology.

13. Engage in personal, professional and career development, to enhance both specialist and

transferable skills in accordance with desired career trajectory.

14. Undertake any other reasonable duties as required by the PI or Head of School.

15. Contribute to the enhancement of the University’s international profile in line with

the University’s Strategic Plan, Inspiring People Changing The World.

Knowledge, Qualifications, Skills, and Experience

Knowledge/Qualifications

Essential:

A1. Normally SCQF level 12 in biological sciences (PhD) plus track record of emerging independence within immunology or similar, or alternatively possess professional qualifications and experience equivalent to PhD level plus the requisite experience.

A2. Knowledge of tissue resident macrophage subsets/phenotypic clusters biology and development in human and mouse.

A3. Sufficient depth of inducible transgenic animal models targeting tissue resident macrophage subsets or fibroblasts subsets, normally including sufficient postdoctoral experience in that field, appropriate to an early career researcher.

A4. Sufficient depth of CRISPR-cas9 based gene editing in primary cells, normally including sufficient postdoctoral experience in that field, appropriate to an early career researcher

A5. A comprehensive and up-to-date knowledge of current tissue multi-omic technologies and analysis pipelines enabling study interactions of tissue resident macrophages with their stromal niche.

Skills

Essential:

C1. Practical skills in transgenic mice crossing, genotyping and running experimental mouse models targeting tissue resident macrophages and/or fibroblasts

C2. Practical knowledge of gene editing in primary cells (e.g. CRISPR-Cas9 based knockings and knockouts)

C3. Practical knowledge of multi-omics tissue analysis.

C4. Practical knowledge of human tissue organoids

C5. Proven ability to deliver quality outputs in a timely and efficient manner.

C6. Ability to demonstrate a degree of independence

C7. Commitment to open research, as appropriate to the discipline, through open data, open code, open educational resources, and practices that support replication.

C8. Excellent interpersonal skills including team working and a collegiate approach.

Experience

Essential:

E1. Experience in conducting and analysing tissue resident macrophages or fibroblasts–oriented animal models, tissue multi-omics data, and human tissue organoids

E2. A proven track record of presenting and publishing research findings in high-quality journals and conferences.

E3. Demonstrated ability to undertake independent research.

E4. Experience in making a leading contribution to academic activities.

E5. A proven commitment to supporting colleagues’ career development and fostering collegiality appropriate to the career stage.

For more information about these projects please see here

Terms and Conditions

Salary will be Grade 7, £41,064 - £46,049 per annum.

This post is full time, and has funding until 31 December 2028

As a valued member of our team, you can expect:

1 A warm welcoming and engaging organisational culture, where your talents are developed and nurtured, and success is celebrated and shared.

2 An excellent employment package with generous terms and conditions including 41 days of leave for full time staff, pension - pensions handbook https://www.gla.ac.uk/myglasgow/payandpensions/pensions/, benefits and discount packages.

3 A flexible approach to working.

4 A commitment to support your health and wellbeing, including a free 6-month UofG Sport membership for all new staff joining the University  https://www.gla.ac.uk/myglasgow/staff/healthwellbeing/.

We believe that we can only reach our full potential through the talents of all. Equality, diversity and inclusion are at the heart of our values. Applications are particularly welcome from across our communities and in particular people from the Black, Asian and Minority Ethnic (BAME) community, and other protected characteristics who are under-represented within the University. Read more on how the University promotes and embeds all aspects of equality and diversity within our community https://www.gla.ac.uk/myglasgow/humanresources/equalitydiversity/.

We endorse the principles of Athena Swan https://www.gla.ac.uk/myglasgow/humanresources/equalitydiversity/athenaswan/ and hold bronze, silver and gold awards across the University.

We are investing in our organisation, and we will invest in you too. Please visit our website https://www.gla.ac.uk/explore/jobs/ for more information.

Closing date: 8 January 2026 at 23:45